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Asthma
Attack Prevention
Current asthma treatment protocols
recommend prevention medications such as an inhaled corticosteroid,
which helps to suppress inflammation and reduces the swelling of the
lining of the airways, in anyone who has frequent (greater than twice a
week) need of relievers or who has severe asthma symptoms.
If asthma symptoms persist,
additional preventive drugs are added until the asthma is
controlled. With the proper use of prevention drugs, asthmatics can
avoid the complications that result from overuse of relief medications.
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Asthma Prevention cont..
Asthma Preventive
Agents include the following:
Inhaled glucocorticoids (fluticasone, budesonide, beclomethasone,
mometasone, flunisolide, and triamcinolone).
Leukotriene modifiers (montelukast, zafirlukast, pranlukast, and
zileuton).
Mast cell stabilizers (cromoglicate (cromolyn), and nedocromil).
Antimuscarinics/anticholinergics (ipratropium, oxitropium), which have a
mixed reliever and preventer effect. (These are rarely used in
preventive treatment of asthma, except in patients who do not tolerate
beta-2-agonists.)
Methylxanthines (theophylline and aminophylline), which are sometimes
considered if sufficient control cannot be achieved with inhaled
glucocorticoids and long-acting β-agonists alone.
Antihistamines, often used to treat allergic symptoms that may underlie
the chronic inflammation. In more severe cases, hyposensitization
("allergy shots") may be recommended.
Omalizumab, an IgE blocker; this can help patients with severe allergic
asthma that does not respond to other drugs. However, it is expensive
and must be injected.
Methotrexate is occasionally used in some difficult-to-treat patients.
If chronic acid indigestion (GERD) contributes to a patient's asthma, it
should also be treated, because it may prolong the respiratory problem.
Asthma Information
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